Stroke includingAtherogenic Index of Plasma (AIP) could be
Stroke is classified as a neurological deficit attributed to an acute focal injury of the central nervous system due to cerebral infarction, intracerebralhemorrhage and subarachnoid hemorrhage 1. It is the third leading cause of death in both developed and developing countries, affecting the people in their “Golden years of life. The prevalence of stroke in India varies from region to region and ranges from 40 to 270 per 100,000 rural population2. The estimated prevalence rates increase from 0.3/1000 for below 45 years age group to 12-20/1000 in the 75-84 years age group3. It has been reported that greater than 10% of patients with stroke due to cerebral infarction are younger than 55 years of age. The prevalence of standard modifiable vascular risk factors in young stroke patients is different from that in older patients Hypertension, heart disease and diabetes mellitus are the most common risk factors among the elderly. In contrast, in young stroke patient, the most common vascular risk factors include dyslipidemia, smoking and hypertension4.Dyslipidemia is well established as being associated with the genesis of ischemic heart disease, but has not been conclusively demonstrated to be associated with the pathogenesis of atherothrombotic stroke or transient ischemic attack (TIA)5. The lack of association between ischemic stroke and plasma lipid components in various studies can be due to diverse pathophysiology of cerebrovascular disease. These Lipid indices includingAtherogenic Index of Plasma (AIP) could be used to diagnose individuals with an elevated risk of cardiovascular disease when the individual parameters in the lipid profile appear normal 6,7. Therefore, in this study, an attempt has been made to compare the lipid profile and lipid indices between young and elderly stroke patients due to varying standard modifiable vascular risk factors in the two age groups.